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| DIAGNOSIS AND TREATMENT GUIDLINES|
|ADVANCED TOPICS IN LYME DISEASE
*************ILADS Evidence-based Lyme Treatment Guidelines
|·Remembering Leslie Wermers. Seven years ago today||2015-11-02 00:00:00|
|·NatCapLyme Board Member Dies from Lyme Disease at 44||2015-04-23 14:05:27|
|·Remembering Leslie Wermers. Six years ago today||2014-11-02 00:00:00|
|·Remembering Leslie Wermers. Five years ago||2013-10-28 18:35:31|
|·Remembering Leslie Wermers. One year ago today.||2009-11-02 20:10:50|
|·Lyme disease patients mourn passing of well known doctor||2009-07-01 04:00:00|
|·All she lost: My sister's battle with Lyme disease||2009-05-19 04:00:00|
|·Laura Treanor, 19, Lyme disease not ruled as cause of death||2009-05-07 04:00:00|
|·Lila Star Smith Harms, 25, dies from complications of Lyme disease||2009-05-05 04:00:00|
|·Lyme Disease Patients Loses a Hero and Friend||2008-11-16 19:57:38|
|·Nancy L. (Scully) Strayer: March 20, 1946 - March 12, 2008||2008-04-12 04:00:00|
|·Bite from tick on holiday led to death leap||2008-04-11 06:49:39|
|·Rugby great, Mike Gregory, loses his battle with Lyme disease||2007-11-24 23:51:00|
|·Missouri teen, 15, dies from Ehrlichiosis||2007-09-04 04:00:00|
|·Steven F. Wells, 45, dies after battle with Lyme disease and ALS||2007-08-14 07:03:39|
|·Bruno C. Malvezzi||2007-07-31 21:06:47|
|·In loving memory of Dr. Edward McNeil||2007-07-24 19:45:00|
|·Lyme disease is a growing problem, Britteny Gallgher, Kansas City, MO||2007-05-24 04:10:00|
|·Lyme Disease Skyrockets In Maryland||2007-05-23 04:00:00|
|·C. Peter Thomas, 46; Sound Engineer||2007-05-21 04:00:00|
|·Jimmy Duarte, gifted musician, charismatic islander, dies at 70||2007-05-17 15:12:03|
|·Obituary: Lyme Disease Advocate Karen Johnson ''Rose'' Rose, 1947 - 2007||2007-04-30 22:50:17|
|·BETH'S QUEST: Family crusades against Lyme disease||2007-04-29 04:00:00|
|·Tick kit distribution aimed at heading off Lyme disease||2007-04-28 12:40:00|
|·Letter to the Editor: In Memory of Lyme Advocate ''Rose''||2007-04-26 11:00:03|
|·Lyme Advocate ''Rose'' Succumbs to Lyme Disease||2007-04-19 18:25:19|
|·Body of Missing Woman with Lyme Disease Found||2007-04-14 21:46:32|
|·Michael Coers won Pulitzer Prize||2007-03-21 10:00:43|
|·E STREETER IN LYME 'SUICIDE'||2007-03-19 12:33:30|
|·Lost to Lyme Lyme disease facts||2007-03-19 04:00:00|
|·Musician remembered as battler against Lyme disease||2007-03-19 04:05:00|
|·Maine Musician Bill Chinnock Dies||2007-03-08 13:45:18|
|·Obituary - Eric von Schmidt - Singer and painter was in Dylan's circle||2007-02-27 11:00:00|
|·JAMES P. KOCH||2007-02-22 00:53:49|
|·Andrew Spielman, 76, Expert on Insect-Borne Diseases, Dies||2006-12-26 04:00:00|
|·Martin Frank Dumke||2006-11-29 04:00:00|
|·Bill Reynolds: For QB Coen, tragedy lies beneath the surface||2006-10-29 04:05:00|
|·Coen plays on without No. 1 fan||2006-10-17 04:00:00|
|·Librarian was dedicated to students, family||2006-09-19 17:02:58|
|·TORMENT OF BRAIN BUG PROF - Alasdair Crockett||2006-09-19 13:43:35|
|·Widow of Lyme disease victim appeals for help||2006-09-18 22:44:57|
|·Professor commits suicide after catching dementia from tick bite||2006-09-17 22:17:12|
|·Tick talk: Family blames member's death on tickborne illness||2006-08-21 04:00:00|
|·Death of York PA area doctor due to Lyme and ALS||2006-04-29 20:40:02|
|·Emmy-winner Scott Brazil dies of ALS and Lyme disease at 50||2006-04-22 11:37:59|
|·Kym Cooper- Dead Woman's Own Letter Tells Her Lyme Disease Story||2006-02-05 14:08:53|
|·Kym Cooper - Worn down by Lyme||2006-01-22 01:56:26|
|·Kym Cooper, 1968-2006, After long battle with Lyme disease||2006-01-19 13:51:02|
|·Tribe leader Francis mourned||2006-01-14 18:22:58|
|·Easton mourns former selectman after fatal accident||2005-12-17 13:04:17|
|·Educator, union leader dies from complications of Lyme disease||2005-12-08 09:25:32|
|·'A TERRIBLE WAY TO GO'||2005-10-22 14:39:56|
|·Leo Bogart, R.I.P. (1921-2005)||2005-10-21 15:55:28|
|·Leo Bogart, 84, Sociologist Who Studied Role of Media in Culture, Is Dead||2005-10-21 15:46:44|
|·Passages: Pat Pepper||2005-10-10 01:11:11|
|·Man loses battle with Lyme disease||2005-10-09 10:37:43|
[ Read Obituaries ]
| U.S. Army, 1983-1996 Lyme Disease Risk Assessments|
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|| Company seeks FDA approval for Nanotrap® "any stage" Lyme test|
November 10, 2015
Lexington, KY USA
By Mac McDonald, BA, MA, CCE
Editor Lymeblog News
"The test is the first highly-sensitive test capable of directly detecting the Lyme protein antigen in a patient at
any stage of infection."
It is now available across the United States for physician offices to order for their patients.
The test is being developed by Ceres with support from the NIH, the Defense Advanced Research Projects Agency (DARPA), the Bill and Melinda Gates foundation, the Department of Homeland Security (DHS), and the Commonwealth of Virginia.
The study, titled: “Application of Nanotrap technology for high
sensitivity measurement of urinary outer surface protein A
carboxyl‐terminus domain in early stage Lyme borreliosis” documents the
development and data behind Ceres’ groundbreaking test for Lyme disease.
The clinical study was led by George Mason University in partnership
with four patient clinics in northern VA and MD. The test is the first
highly-sensitive urine based test capable of directly detecting the Lyme
protein antigen in a patient at any stage of infection. It is now
available across the United States for physician offices to order for
- Ceres Nanosciences, Inc.
(Ceres) announced today the publication of a three year, 300-person clinical study in the Journal of Translational Medicine.
Additionally, to accelerate the expansion of Ceres’ Lyme test program, Ceres has been awarded funding
from the Virginia Biosciences Health Research Corporation (VBHRC) to adapt the test to a new format for FDA approval and to incorporate additional testing capabilities for other tick-borne diseases. Ceres, a biotechnology company located in northern Virginia, has developed and commercialized a novel nanoparticle technology, the “Nanotrap®”, which provides powerful biofluid sample processing capabilities for cutting edge diagnostic applications and sample handling needs.
The Nanotrap technology was invented at George Mason University under funding from the National Institutes of Health (NIH) for biomarker discovery applications. Currently it is being developed into commercial products by Ceres with support from the NIH, the Defense Advanced Research Projects Agency (DARPA), the Bill and Melinda Gates foundation, the Department of Homeland Security (DHS), and the Commonwealth of Virginia.
“We are very excited about the Nanotrap Lyme Antigen test. It is the first urine based test that directly measures the presence of proteins from the Lyme pathogen itself. This test can render an accurate and objective measurement of the presence of Lyme infection at any stage of infection,” said Ross Dunlap, Chief Executive Officer of Ceres. “Without the Nanotrap technology as an upfront sample concentration step, this assay would not be possible. The Nanotrap technology is contributing already to the medical field’s understanding of Lyme disease, and other infectious diseases, leading to better tests, vaccines, and therapies.”
“Our test offers a much higher sensitivity and specificity compared to existing Lyme testing methods. We are measuring a Lyme surface protein region that is conserved across all the known Lyme species and strains that infect patients in America and Europe. The Nanotrap particles enhance the sensitivity of this test one hundred fold.” said Dr. Lance Liotta, principal investigator of the Lyme Disease Clinical Trial and Co-Director of the Center for Applied Proteomics and Molecular Medicine at George Mason University and co-founder of Ceres.
The Nanotrap® LA (Lyme Antigen) Test kit may be ordered through any participating physicians’ offices and clinical labs. If your doctor does not offer the test, you may order a kit from the Ceres Nanosciences Lyme Antigen Collection Kit Order Site or send an email to Ceres Nanosciences at firstname.lastname@example.org with your full name, phone number, and an address where the kit should be mailed. Ceres Nanosciences will send a free collection kit with details for providing a sample to their lab and how to order the test through your physicians office. Ceres Nanosciences will only process tests that are ordered through a physician’s office.
The Lyme Antigen Test costs ...
Note: Related stories:
New Test Shows Potential for Detecting Active Cases of Lyme Disease, Lymeblog News, February 24. 2015
Posted by Editor on Wednesday, November 11 @ 13:49:02 EST (274 reads)|
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|| Obituaries: Remembering Leslie Wermers. Seven years ago today|
Lexington, KY USA
By LymeBlog News Staff
~You've touched Countless Lives in so Many Beautiful Ways~She Was Always A Loving and Giving Sister; Daughter; Life- Partner; Jayde's Lessie; Ralphie & Dudley's Mommy; Cherished Lyme Patient Advocate; Aunt; Niece; Cousin; & Friend.
Here is an excerpt from the beautiful tribute that Andy Abrahams Wilson wrote in memory of Leslie.
Andy is the Producer/Director of the Powerful Lyme Disease Documentary,"Under Our Skin".
"The Lyme community has lost an important hero and friend–and so did I. Leslie Wermers, 41, died from heart failure in her sleep on November 2nd, 2008."
"It is hard to imagine Leslie’s heart giving out, because for anyone who knew her she was all heart."
"A dear friend to so many and a tireless worker on behalf of the Minnesota and national Lyme communities, Leslie gave everything she had to help others who were sick. And everything she had was an abundant reserve of love and support–even as her own health waned." Andy Abrahams Wilson, Producer/Director, UNDER OUR SKIN Click Here to read the entire tribute and to watch Leslie's interview excerpt from "Under Our Skin".
Posted by Editor on Monday, November 02 @ 00:00:00 EST (450 reads)|
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|| Lyme Disease Advocates Say CDC Allows Questionable Group to Dictate Treatment|
October 20, 2015
Lexington, KY USA
By Mac McDonald, BA, MA, CCE
Editor Lymeblog News
The Centers for Disease and Control Prevention (CDC) group responsible for policy on Lyme disease violates federal law by extending preferential treatment to the Infectious Diseases Society of America (IDSA) says a petition created by a group of Lyme patient advocates.
The petition to End Preferential Treatment of the IDSA Guidelines for Lyme Disease
was filed with the CDC’s Bacterial Diseases Branch on Wednesday, October 14.
Graphic by Alison Childs of Lymestats
The petitioners are exercising their First Amendment right to petition the government for “a redress of grievances,” along with a more specific right added by the Administrative Procedure Act, which provides “interested persons” with the “right to petition for the issuance, amendment, or repeal of a rule.”
"Why does the CDC, a public agency tasked with protecting the health of US taxpayers, promulgate the IDSA guidelines as policy, particularly when it can be demonstrated that the guidelines authors disallow, ignore, or reject a very large body of scientific evidence that contradicts their narrow view of this disease?"
The petitioners claim that “because of restrictions imposed by the critically flawed IDSA guidelines promoted by CDC, thousands of chronically ill patients
are harmed by misdiagnosis and denial of medically necessary treatment.
CDC’s failure to provide equivalent exposure for more recent guidelines
from the International Lyme and Associated Diseases Society
(ILADS) compounds the harm by omitting information about evidence-based
treatments that could help these severely ill patients recover from
this devastating disease.”
In addition, these advocates want to ...
Posted by Editor on Wednesday, October 21 @ 13:25:14 EDT (736 reads)|
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|| UMass Medical School Developing Lyme disease Vaccine|
October 8, 2015
Lexington, KY USA
By Mac McDonald, MA, CCE
Editor Lymeblog News
New research to be presented at infectious disease conference
IDWeek; Monoclonal antibodies reactive against a broad range of Borrelia
species in studies
Scientists at UMass Medical
School’s MassBiologics are developing a pre-exposure prophylaxis that
prevents tick-transmitted infection of Lyme disease, a breakthrough that
could lead to seasonal prevention against the most common tick-borne
infection in North America.
Scientists at UMass Medical School’s MassBiologics are developing a
pre-exposure prophylaxis that prevents tick-transmitted infection of
Lyme disease, a breakthrough that could lead to seasonal prevention
against the most common tick-borne infection in North America. The
research will be presented on Friday, Oct. 9, in San Diego at IDWeek
2015TM, the annual meeting of the Infectious Disease Society of America,
the Society for Healthcare Epidemiology of America, the HIV Medicine
Association and the Pediatric Infectious Diseases Society. The research
report details the effectiveness of a monoclonal antibody in targeting
the bacteria that causes Lyme disease in mice, the most common natural
reservoir for the bacteria.
“In our strategy, individuals would receive an injection in the
spring of a single human monoclonal antibody targeting a protein on the
surface of the bacteria that would provide immediate protection against
Lyme disease and that protection would last for about 6 months, which is
the risk period when the ticks that transmit Lyme disease are active,”
said Mark S. Klempner, MD, executive vice chancellor of MassBiologics
and professor of medicine at UMMS. “This is the same strategy—a
monoclonal antibody that targets an infectious disease—that is used to
prevent one of the most severe forms of pneumonia in premature infants
called respiratory syncytial virus (RSV). With over 15 years of data
showing the safety and effectiveness of administering this human
monoclonal antibody (Synagis ®) to these most vulnerable babies, we have
observed a very high level of protection with virtually no short or
longer term serious adverse reactions.”
MassBiologics discovers, develops and manufactures biologic medicines
that improve the lives of the people in the Commonwealth of
Massachusetts. As the only non-profit, medical-school-affiliated,
FDA-licensed manufacturer of vaccines and other biologic medicines like
monoclonal antibodies, MassBiologics has a particular focus on public
Lyme disease is the most common tick-borne infection in North
American and Eurasian countries with temperate climates. It is spread
Posted by Editor on Thursday, October 08 @ 16:13:50 EDT (613 reads)|
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|| ILADS treatment guidelines now on National Guidelines Clearinghouse|
“Exclusion of patient interests and disregard for competing guidelines makes the IDSA review process untrustworthy,”
Dr. Daniel Cameron, President of ILADS and lead author of the ILADS guidelines.
(Bethesda, MD Sept 21, 2015) — The Centers for Disease Control and Prevention (CDC) estimates that more than 300,000 new cases of Lyme disease occur annually in the US.
The International Lyme and Associated Diseases Society (ILADS) has
criticized the Lyme guidelines review panel of the Infectious Diseases
Society of America (IDSA) for excluding patient interests and
disregarding competing guidelines in its review plan.
The ILADS guidelines include share medical decision making and take patient
values into consideration.
Lorraine Johnson, JD, MBA, a coauthor and
Chief Executive Officer of LymeDisease.org, said “A lot of the treatment
decisions in Lyme disease depend on trade-offs. How sick is the
patient, how invasive is the treatment, what is valued by the patient?
Patients need to understand the risks and benefits of treatment options
to make informed medical choices. These guidelines provide that
ILADS is proud to announce their guidelines are now available on the National Guidelines Clearinghouse (NGC) website.
ILADS guidelines, Evidence Assessments and Guideline Recommendations in
Lyme disease: The Clinical Management of Known Tick Bites, Erythema
Migrans Rashes and Persistent Disease” bring the latest scientific
evidence to bear on the management of the illness.
The National Guidelines Clearinghouse (NGC) is an initiative of the Agency for Healthcare Research and Quality (AHRQ), under the umbrella of the U.S. Department of Health and Human Services. The NGC recently adopted the Institute of Medicine (IOM) standards for developing trustworthy guidelines, which define the highest level of excellence that a guideline can achieve. Guidelines posted on the NGC website must now satisfy these standards. Thus, the inclusion of ILADS’s peer reviewed guidelines on the NGC website demonstrates that they meet the ...
Posted by Editor on Tuesday, September 22 @ 12:26:55 EDT (771 reads)|
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